Evodia unripe fruit (Wu-zhu-yu) – The Herb Used in Traditional Systems to Support Normal Warmth and Stomach ComfortEvodia unripe fruit (Wu-zhu-yu), also known as "Evodia Fruit" or "Tetradium Fruit," is the traditional Chinese name for the dried nearly-ripe fruits of Evodia rutaecarpa (syn. Tetradium ruticarpum), a very warm, acrid herb from the citrus-like family that has been part of traditional Chinese herbal systems for over 2000 years. This very warm, bitter-acrid herb is particularly known for its ability to promote normal body warmth, expel normal cold from the digestive system, regulate normal Qi flow, relieve normal pain and support normal nausea/vomiting – making it an ideal choice for people with a tendency toward normal cold patterns, normal stomach discomfort, normal dysmenorrhea and normal pattern-based headaches.Traditional Understanding in TCM SystemsWithin traditional Chinese medicine, evodia unripe fruit (Wu-zhu-yu) is described as a very warm, bitter-acrid herb with strong interior-warming effect. In the TCM theoretical framework, it acts on the so‑called Spleen, Stomach, Liver and Kidney meridians. According to this traditional description, evodia unripe fruit (Wu-zhu-yu) specializes in normal "cold expulsion," helps "normal Qi regulation," "normal pain relief" and "normal nausea control" – crucial TCM concepts for normal digestive warmth and normal comfort.Evodia unripe fruit (Wu-zhu-yu) is seen in TCM as a classical "warmth promoter and cold expeller" – one of the most directly acting warm herbs. It is traditionally used to promote normal body warmth, support normal digestive comfort, ease normal cold-pattern pain, regulate normal nausea and vomiting and support normal menstruation management.Special Property: Very Warm and Directly AcridEvodia unripe fruit (Wu-zhu-yu) distinguishes itself by its very warm nature and very direct "cold-expelling" effect. This warm-acrid character means it effectively addresses normal cold patterns and restores normal digestive warmth without weakening.Botanical Composition and ResearchEvodia unripe fruit (Wu-zhu-yu) contains over 100 bioactive compounds, of which the main ones are:Evodiamine (indole alkaloid – characteristic component, 0.24–1.2%)Rutaecarpine (related alkaloid – thermogenic component)Dehydroevodiamine (characteristic alkaloid)Essential oilsFlavonoids (quercetin, kaempferol)Polyphenols and tanninsModern scientific research shows that evodia unripe fruit (Wu-zhu-yu) components can offer diverse benefits:Normal warmth promotion: Studies show that evodiamine and rutaecarpine can influence normal thermogenesis – likely the classical "warming" TCM action. This occurs partly through TRPV1 receptor activation (capsaicin-like mechanism).Normal cold expulsion: Research suggests that certain components can address normal cold patterns without weakening the body.Normal stomach support: Studies show that certain components can support normal stomach function and help regulate normal acid production.Normal pain relief: Alkaloids have demonstrated pain-relieving properties, especially for cold-pattern-related pain.Normal nausea control: Traditionally used and scientifically supported for normal nausea relief.Normal Qi regulation: Acrid components can support normal Qi movement.Anti-inflammatory action: Polyphenols can help maintain normal inflammation balance.Antimicrobial potential: Alkaloids have demonstrated antimicrobial activity.Traditional Applications – TCM ContextIn traditional TCM formulas, evodia unripe fruit (Wu-zhu-yu) is classically used in situations described as:Normal cold-pattern stomach pain (relieved by warmth/pressure)Normal dysmenorrhea with cold characterNormal vomiting or nausea with cold characterNormal relief of nocturnal awakening/nocturia with cold characterNormal migraine or vertex headaches with cold characterNormal indigestion or food stagnation with cold characterNormal diarrhea with cold characterNormal foot coldness or normal aversion to coldNormal reduced appetite with cold characterNormal menstrual patterns with cold characterThese are traditionalist descriptions that form part of the TCM thinking system and must not be equated with medical diagnoses in the sense of European medicinal product law.Very Warm and Cold-Expelling CharacterEvodia unripe fruit (Wu-zhu-yu) is traditionally seen as a "very warm" and "cold-expelling" herb – which effectively addresses normal cold patterns and restores normal body warmth. This makes it particularly suitable for people with a tendency toward normal cold-pattern symptoms.Classical Formula: Wu Zhu Yu TangA famous classical application is in the formula "Wu Zhu Yu Tang" (Evodia Decoction), traditionally used for over 1800 years (introduced in 220 AD) for normal cold-pattern stomach pain, normal vomiting and normal nausea. This very famous formula contains evodia unripe fruit (Wu-zhu-yu) as a core ingredient, combined with Sheng Jiang (fresh ginger), Ren Shen (ginseng) and Da Zao (jujube).Other Classical Formulas:Wen Jing Tang: for normal menstrual patterns with cold characterZuo Jin Wan (complementary): for normal nausea control (Wu-zhu-yu as deputy)Xiao Yao San (complementary): can contain evodia unripe fruit (Wu-zhu-yu) for normal dysmenorrheaPreparation and DosageEvodia unripe fruit (Wu-zhu-yu) is traditionally:Built into formulasTraditional dosage: 3–6g per formulaNEVER as standalone herb for daily independent useAlways in balanced formulasCAUTION: NOT FOR HEAT PATTERNS OR PREGNANCYEvodia unripe fruit (Wu-zhu-yu) must NOT be used by:Individuals with normal heat patterns (dry mouth, night sweats, redness)Pregnant women (without professional supervision – can have uterus effects)Individuals on certain medications (e.g., certain anticoagulants)Individuals with serious gastric ulcer diseaseCAUTION: HEPATOTOXICITY WITH OVERDOSAGEEvodia unripe fruit (Wu-zhu-yu) contains rutaecarpine, which in very high isolated doses can cause liver damage. This is however NOT a problem at traditional TCM dosage (3–6g) in formulas, where:The whole plant matrix provides protective effectsThe dosage is very lowIt is always used in balanced formulasProfessional supervision is essentialSeasonality and Daily UseEvodia unripe fruit (Wu-zhu-yu) is traditionally used especially in cold seasons or for cold-pattern symptoms. It must NEVER be used as daily standalone herb without professional supervision.Well-being and Daily UseEvodia unripe fruit (Wu-zhu-yu) is valued by modern users as part of professional TCM formulas for normal warmth support, normal stomach health and normal pain relief. This herb is NOT suitable for independent daily standalone use.Many users see evodia unripe fruit (Wu-zhu-yu) as part of professional TCM formulas for normal health – as a very warm, directly acting element for normal cold-pattern support, ALWAYS under the guidance of a qualified TCM doctor.Very Safe Profile (At Professional Dosage)Evodia unripe fruit (Wu-zhu-yu) is known as one of the safest warm herbs in TCM when used at traditional dosage (3–6g) under professional supervision. Toxicity risks arise ONLY with severe overdosing of isolated components.CAUTIOUS NOTE FOR THE CONSUMERThis product is a dietary supplement for professional TCM use. TCM terms such as Cold Expulsion, Warmth Promotion, Normal Qi Regulation are system concepts that form part of a traditional thinking system and must not be directly equated with anatomical structures or disease explanations in modern medicine.If you have persistent cold-pattern symptoms, severe stomach pain or normal vomiting problems, you should always consult a qualified TCM doctor or medical expert BEFORE using this herb in formulas.CAUTION: Not for independent standalone use – professional supervision essential. Not for heat patterns.

