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Main benefits

The Synergy Effect:

A complex of live active cultures, delivering 22.5 billion colony-forming units (CFU) across multiple diverse bacterial strains, works synergistically to establish a thriving microbial community within the intestines. This high-potency blend is designed to support the intestinal barrier function and help maintain an environment less favourable to the colonization of undesirable microorganisms. As the live cultures adhere to the intestinal lining and create a protective biofilm, they engage in the production of beneficial metabolites—including short-chain fatty acids—that naturally nourish the intestinal cells and support normal immune function. By promoting a balanced internal ecosystem and supporting normal digestion, this live culture complex creates optimal conditions for efficient nutrient absorption, stable energy levels, and digestive comfort—working synergistically to maintain overall wellness and constitutional vitality from the core outwards.

Connection to Traditional Chinese Medicine:

From a TCM perspective, the entire digestive ecosystem is the domain of the Spleen and Stomach, the central organs of transformation and transportation responsible for converting food and drink into Qi and Blood. A balanced and thriving intestinal microbiota directly supports the function of Spleen Qi. When Spleen Qi is deficient, the digestive system loses its transformative power, leading to fatigue, weak digestion, and the accumulation of turbid fluids known as Phlegm-Dampness (often manifesting as bloating, sluggishness, and brain fog). By harmonizing the gut environment, this high-potency live culture complex helps to "dry" and clear Dampness indirectly by restoring the Spleen’s innate ability to process fluids and nutrients efficiently. A robust microbiome supports the Middle Burner’s transformative fire, helping to resolve the heavy, stagnant nature of Phlegm while rebuilding the clear, ascending energy of the Spleen. The Spleen in Chinese Medicine is the root of post-heaven Qi, responsible for food transformation, nutrient assimilation, and maintaining healthy immunity—functions that are fundamentally dependent on a balanced gut ecosystem. This formula helps maintain the vital connections between digestive resilience, the clearance of damp stagnation, and the stable foundation of Qi that supports daily vitality.

This product complies with EU Regulation (EC) No 1924/2006 on nutrition and health claims and meets NVWA requirements for food supplements in the Netherlands.


Zhenatura.com TCM: Herbal dietary supplements of Traditional Chinese Medicine origine according to European standards!

  • 60 tablets per bottle
  • Less fillers and binders
  • No pharmaceuticals or dyes
  • Thorough lab testing (heavy metals, pesticides etc.)
  • Always made in controlled cGMP certified facility
  • Unbeatable value
  • European brand
TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. We advice always to use minimum 1 packing and then evaluate with your prescriber!
This product is a dietary (food) supplement, to be taken as directed by a qualified practitioner. It is not intended to treat, cure, diagnose or prevent any disease. Not to replace a varied diet. Not to be taken if nursing or if pregnant. Not to be consumed continuously for longer than 3 months.

Common uses

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Information for professionals

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Zhenatura Active Live Culture Complex 22.5b CFU (Qi and Spleen Qi Deficiency, Phlegm-Damp) is based on the foundational principles of Orthomolecular Medicine and Evidence-Based Microbiome Science, rooted in the systematic microbiological investigations of beneficial intestinal flora from the late 19th and early 20th centuries. Probiotic science was pioneered by Russian-French zoologist and Nobel laureate Élie Metchnikoff, who proposed in his 1907 landmark publication The Prolongation of Life that the consumption of lactic acid bacteria — particularly those found in fermented dairy — could suppress putrefactive intestinal microorganisms and positively modulate host health and longevity, while the formal classification of Lactobacillus acidophilus was established by Ernst Moro in 1900 and the term "probiotic" itself — meaning "for life" — was coined by Werner Kollath in 1953 and later refined by Lilly and Stillwell in 1965, culminating in the internationally adopted FAO/WHO definition of 2001 describing live microorganisms that, when administered in adequate amounts, confer a health benefit on the host. Within scientific gastroenterological and immunological literature, this specific multi-strain Live Culture Complex at 22.5 billion CFU — comprising clinically validated strains across Lactobacillus, Bifidobacterium, and Streptococcus thermophilus species — is described as a strategy to "restore and diversify commensal gut microbiota," "strengthen intestinal epithelial barrier integrity through tight junction modulation," and "regulate mucosal immune homeostasis via toll-like receptor signalling and secretory IgA production" in accordance with current gastroenterological, immunological, and metabolic biochemical theory. These descriptions belong to the modern empirical system of microbiome science and clinical nutrition and refer to the support of validated physiological mechanisms rather than the "tonification of Spleen Qi," "transformation of Phlegm-Damp," or "fortification of Zhong Qi" found in traditional energetic systems.

1
Irritable Bowel Syndrome (IBS) & Digestion — Spleen Qi Deficiency
https://www.nature.com/articles/s41598-024-60029-2

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • Randomized, double-blind clinical trials demonstrate that multi-strain probiotic supplementation significantly improves gastrointestinal symptoms in IBS patients, resulting in substantial drops in symptom severity scores (IBS-SSS), including reductions in bloating, abdominal pain, and altered bowel habits (Research Link: Nature 2024).

  • Probiotic interventions restore gut microbiota diversity and improve perceived quality of life, increasing the prevalence of clinical remission in functional gastrointestinal disorders (Research Link: Nature 2024).​

  • In TCM, this directly corresponds to tonifying Spleen Qi. The Spleen is responsible for the "transformation and transportation" of nutrients; by restoring the gut barrier and microbiome, live cultures correct the fundamental Spleen Qi Deficiency that causes bloating, loose stools, and poor digestive motility.


2
Metabolic Syndrome & Systemic Inflammation — Resolving Phlegm-Damp
https://pmc.ncbi.nlm.nih.gov/articles/PMC7019472/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • Systematic reviews and RCTs evaluating probiotic intake in patients with Metabolic Syndrome (MetS) report clinical improvements in body mass index (BMI), blood pressure, glucose metabolism, and lipid profiles (Research Link: PMC7019472).


3
Metabolic Syndrome & Systemic Inflammation — Resolving Phlegm-Damp
https://pubmed.ncbi.nlm.nih.gov/32417946/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • Supplementation with Lactobacillus strains effectively decreases systemic inflammatory biomarkers, downregulating pro-inflammatory cytokines such as IL-6, TNF-α, and CRP while improving insulin resistance in elderly populations.

  • In TCM, metabolic syndrome, obesity, and hyperlipidemia are viewed as accumulations of Phlegm-Dampness. Probiotics help to transform these turbid fluids by supporting metabolic pathways, thereby resolving the Dampness that obstructs the Middle Jiao.


4
Gut-Brain Axis, Fatigue, and Immunity — Qi Deficiency & Phlegm-Damp
https://pmc.ncbi.nlm.nih.gov/articles/PMC10221065/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • Clinical studies indicate that probiotics are a promising intervention for patients with post-infectious fatigue, significantly improving energy levels and reducing physical limitations by modulating the gut-brain axis.


5
Gut-Brain Axis, Fatigue, and Immunity — Qi Deficiency & Phlegm-Damp
https://pmc.ncbi.nlm.nih.gov/articles/PMC12883760/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • By enhancing short-chain fatty acid (SCFA) metabolism and restoring the integrity of both the intestinal and blood-brain barriers, live cultures attenuate microglial activation and neuroinflammation, which alleviates mental fatigue and depression (Research Link: PMC12883760).​

  • In TCM, this dual action lifts Phlegm-Dampness from the mind (clearing brain fog and improving mental vitality) while concurrently tonifying systemic Qi to combat severe, lingering fatigue.

For Active Live Culture Complex 22.5b CFU, take 1 tablet 1 time per day. These should be taken before a meal.

Total pieces in package: 60 tablets

Dosage: 1 tablet

Frequency: 1 time a day before a meal


Side effects

Headache

Mild Dryness

Mild Fatigue or "Foggy" Feeling

Mild gastrointestinal discomfort

Nausea

Thirst


Allergies

Individuals allergic to any of the herbal ingredients should avoid use. Discontinue immediately if any allergic reactions, such as rash, itching, or swelling, occur.

Casein protein allergy

Corn allergy

Exacerbation of inflammatory responses

Fructooligosaccharides (FOS) and prebiotics

Gelatin

Histamine-producing bacterial strains

Immunocompromised individuals and severe underlying conditions

SIBO and gut dysbiosis exacerbation

Soy


Avoid medicine interactions

Antibiotics

Antifungal Medications

Immunosuppressants

Medications Affected by Changes in Intestinal pH

Medications Metabolized by Gut Microbiota

Medications with Narrow Therapeutic Windows


Precautions

Do not use if pregnant or breastfeeding.

Consult your herbalist or physician before use if you are taking other medications or receiving other medical treatments.

Keep out of reach of children.


Indemnification

This product is a dietary supplement, and should only be used as prescribed by a qualified acupuncturist, herbalist, phyto- or TCM therapist. This product is not intended to diagnose, treat, prevent or cure any disease. Always consult a qualified doctor or healthcare professional before using this. A healthy lifestyle is important, as is a varied, balanced diet, for which supplements are not a substitute.

TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. 1 packing adviced and then evaluate with your prescriber!

Allergies

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Formula types

Ingredients

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