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Main benefits

The Synergy Effect:

While Vitamin D3 works to enhance calcium absorption from your intestines into your bloodstream, Vitamin K2 simultaneously acts as a director, guiding that calcium away from soft tissues and arteries and toward your bones and teeth where it belongs. Together, they create a balanced system that supports bone mineralization, maintains healthy cardiovascular function, and supports the immune system. By regulating calcium metabolism and ensuring its proper utilization, the D3 and K2 complex creates optimal conditions for skeletal strength, cardiovascular health, and immune resilience, working synergistically to maintain overall wellness and constitutional vitality.

Connection to Traditional Chinese Medicine:

From a TCM perspective, the Kidneys store Jing (Essence), which is the foundation of all Yin and Yang in the body and governs the bones, marrow, and teeth. A balanced intake of Vitamin D3 and K2 supports Kidney function, helping to strengthen the bones and teeth while promoting a strong physical constitution and vitality. By harmonizing calcium metabolism and supporting bone density, this nutrient complex indirectly tonifies Kidney Jing, supports the body's foundational energy, and maintains the dynamic balance of the Water element which is central to healthy aging and structural integrity. The Kidneys in Chinese Medicine are responsible for bone health, the production of marrow, and the maintenance of deep constitutional strength, functions that are fundamentally supported by optimal calcium regulation. This formula helps maintain the vital connections between skeletal health, cardiovascular flow, and the stable foundation of Jing that supports long-term vitality.

This product complies with EU Regulation (EC) No 1924/2006 on nutrition and health claims and meets NVWA requirements for food supplements in the Netherlands.


Zhenatura.com TCM: Herbal dietary supplements of Traditional Chinese Medicine origine according to European standards!

  • 90 tablets per bottle
  • Less fillers and binders
  • No pharmaceuticals or dyes
  • Thorough lab testing (heavy metals, pesticides etc.)
  • Always made in controlled cGMP certified facility
  • Unbeatable value
  • European brand
TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. We advice always to use minimum 1 packing and then evaluate with your prescriber!
This product is a dietary (food) supplement, to be taken as directed by a qualified practitioner. It is not intended to treat, cure, diagnose or prevent any disease. Not to replace a varied diet. Not to be taken if nursing or if pregnant. Not to be consumed continuously for longer than 3 months.

Common uses

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Information for professionals

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Zhenatura Vitamin D3 and K2 (Yang and Yin Deficiency) is based on the foundational principles of Orthomolecular Medicine, rooted in the seminal vitamin discoveries of the early 20th century. Vitamin D was first chemically characterized in the 1920s as a critical factor for skeletal development, followed by the identification of Vitamin K by Henrik Dam in 1929. Within scientific nutritional literature, this specific pairing of bioactive forms, including Cholecalciferol (Vitamin D3) and Menaquinone-7 (Vitamin K2), is described as a strategy to “optimize calcium utilization,” “activate osteocalcin,” and “ensure vascular safety” in accordance with biochemical theory. These descriptions belong to the modern empirical system of nutritional science and refer to the support of validated physiological mechanisms rather than the "balancing of Qi" found in traditional energetic systems.

1
Severe Coronary Artery Calcification (CAC) – RCT Protocol (BMJ Open, NCT05500443)
https://www.bohrium.com/paper-details/effects-of-vitamins-k2-and-d3-supplementation-in-patients-with-severe-coronary-artery-calcification-a-study-protocol-for-a-randomised-controlled-trial/886821456556589541-7179

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • Multicentre, double‑blind RCT of 400 men and women with CAC score ≥400, randomized to vitamin K2 (720 µg/day) + D3 (25 µg/day) or placebo for 2 years.​

  • Primary outcome: progression in CAC score on cardiac CT at 24 months; secondary outcomes include plaque composition and cardiac events; rationale is that D3 stimulates synthesis and K2 activates calcification‑inhibiting matrix Gla protein.​


2
Spinal Fusion in Osteoporotic Patients – Prospective Clinical Trial (Scientific Reports, 2025)
https://www.nature.com/articles/s41598-025-99922-9

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

  • Prospective clinical trial in patients with osteoporosis undergoing endoscopic lumbar interbody fusion (ELIF) compared vitamin K2 + D3 adjunctive therapy to standard D3 + calcium alone.​

  • The K2 + D3 group showed significantly higher spinal fusion rates and more favorable changes in bone metabolism markers (notably higher P1NP at 3 months), indicating enhanced bone formation without a significant between‑group difference in bone resorption marker β‑CROSS.​

For Vitamin D3 and K2, take 1 tablet 1 time per day. These should be taken before or after meal.

Total pieces in package: 90 tablets

Dosage: 1 tablet

Frequency: 1 time a day before or after meal


Side effects

Appetite loss

Gastrointestinal discomfort

Headache

Kidney complications


Allergies

Individuals allergic to any of the herbal ingredients should avoid use. Discontinue immediately if any allergic reactions, such as rash, itching, or swelling, occur.

Corn or Starch Allergy

Gluten Allergy

Nuts

Soy

Sulphites


Avoid medicine interactions

Anticoagulants

Anticonvulsants or Anti-Seizure Medications

Cardiac Glycosides

Cholesterol-lowering drugs

Corticosteroids

Liver-metabolized drugs

Thiazide Diuretics


Precautions

Do not use if pregnant or breastfeeding.

Keep out of reach of children.

Consult your herbalist or physician before use if you are taking other medications or receiving other medical treatments.


Indemnification

This product is a dietary supplement, and should only be used as prescribed by a qualified acupuncturist, herbalist, phyto- or TCM therapist. This product is not intended to diagnose, treat, prevent or cure any disease. Always consult a qualified doctor or healthcare professional before using this. A healthy lifestyle is important, as is a varied, balanced diet, for which supplements are not a substitute.

TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. 0 packings adviced and then evaluate with your prescriber!

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