Main benefits
  • Pattern identification: Traditionally used for the TCM pattern of Kidney Yang deficiency with Essence and Blood depletion, where the body’s warming and motivating force (“Ming Men fire”) is weak and can no longer effectively support growth, reproduction, and movement.

  • Name and core idea: [translate:右归饮] means “Right‑Returning Drink,” referring to “returning” or restoring the Right Kidney (associated with Yang and Fire) so that Yang can again warm and drive the functions of all organs. It is considered the milder, decoction counterpart to the stronger pill formula You Gui Wan.

  • Main actions in TCM: The formula warms and tonifies Kidney Yang, replenishes Essence (Jing), and nourishes Blood, with a gentler, more fluid‑supporting profile than purely hot Yang‑rescuing prescriptions. It is used when deficiency is clear but not yet at a “collapse” stage.

  • Typical core ingredients and roles (TCM functions): Yang‑warming, Essence‑supporting: Herbs such as Rou Gui (Cinnamon Bark) and Fu Zi (Aconite, often at lower/safer dose or omitted in modern versions) warm the Ming Men fire and restore Kidney Yang. Essence and Blood tonification: Shu Di Huang (Prepared Rehmannia), Shan Zhu Yu (Cornus), and Gou Qi Zi (Lycium) nourish Kidney and Liver Essence/Blood. Assist Spleen and consolidate: Shan Yao (Chinese Yam) and sometimes Du Zhong (Eucommia) or Tu Si Zi (Dodder Seed) strengthen the Spleen–Kidney axis and support the lower back and knees. Harmonizing and Qi support: Mild Qi‑tonics and harmonizers like Gan Cao (Licorice) round out the prescription so tonification is well tolerated in weak digestion.

  • Typical TCM presentation: Classical descriptions include coldness and weakness of the lower back and knees, fatigue, a preference for warmth, diminished drive or vigor, possible nocturnal emissions or decreased reproductive function, pale and swollen tongue, and deep, weak pulse—all interpreted as Kidney Yang and Jing deficiency, not as specific Western diseases.

  • Position among Kidney formulas: Compared with Liu Wei Di Huang Wan or Zuo Gui Wan, which focus on Yin/Essence, You Gui Wan emphasizes Yang and Fire. You Gui Wan is a lighter, decoction‑type option for patients who need Yang support but still have some fluids and cannot tolerate very hot, highly concentrated pills.

  • Classical heritage: Attributed to the Ming/Qing‑era warm‑tonic school (following Li Dong‑yuan and later commentators), You Gui Wan is recognized in modern TCM as a key gentle formula for chronic Kidney Yang deficiency patterns that require long‑term, steady reinforcement rather than acute Yang rescue.


Zhenatura.com TCM: Herbal dietary supplements of Traditional Chinese Medicine origine according to European standards!

  • Strength 10:1
  • 120 tablets per bottle
  • Double or Triple the strength as regular brands
  • Less fillers and binders
  • No pharmaceuticals or dyes
  • Thorough lab testing (heavy metals, pesticides etc.)
  • Always made in controlled cGMP certified facility
  • Unbeatable value
  • European brand
TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. We advice always to use minimum 1 packing and then evaluate with your prescriber!
This product is a dietary (food) supplement, to be taken as directed by a qualified practitioner. It is not intended to treat, cure, diagnose or prevent any disease. Not to replace a varied diet. Not to be taken if nursing or if pregnant. Not to be consumed continuously for longer than 3 months.

Common uses

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Information for professionals

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Zhenatura You Gui Wan Extra Strong is based on the classical You Gui Wan (“Restore the Right Decoction”) first recorded in the Ming‑dynasty text Jing Yue Quan Shu by Zhang Jing‑Yue. Within the traditional TCM framework, the combination of botanicals such as Rehmannia, Cinnamon, and Goji Berry was described as a method to “warm Yang,” “nourish Essence (Jing),” and “support balance between Yin and Yang.” These descriptions refer exclusively to traditional Chinese theoretical concepts and do not correspond to modern anatomy, endocrinology, or scientifically verified physiological effects.

1
Musculoskeletal Disorders: Knee Osteoarthritis (KOA)
https://pubmed.ncbi.nlm.nih.gov/39674342/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Protective Effects in KOA Models

  • Recent experimental studies show that You Gui Yin significantly alleviates cartilage damage, reduces apoptosis and pyroptosis in cartilage tissues, and exhibits strong anti-oxidant and anti-inflammatory activities in knee osteoarthritis models.

  • YGYP drives macrophage polarization from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype, both in vitro and in vivo.

  • Treatment led to reduced oxidative sdfdftress markers, lower levels of inflammatory cytokines, and improved cartilage histopathology.

  • In cell co-culture systems, YGYP improved chondrocyte viability and reduced inflammation and cartilage degradation.


2
Pharmacokinetics and Drug Interactions
https://pmc.ncbi.nlm.nih.gov/articles/PMC7244958/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Findings:

  • Impact on Cytochrome P450 Enzymes

  • Animal studies demonstrate that You Gui Yin can induce the activity of hepatic CYP2C9, CYP2C19, and CYP3A4 enzymes.

  • High doses of YGYP decreased plasma concentrations of drugs metabolized by these enzymes and increased their clearance.

  • This suggests that YGYP may alter the metabolism of co-administered medications, underscoring the need for caution when combining with drugs processed by these pathways.


3
Immune Regulation and Anti-Inflammatory Effects
https://www.sciencedirect.com/science/article/abs/pii/S1567576905000433

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Immunomodulatory Activity

Preclinical research indicates that YGYP protects against immunosuppression by enhancing transcription of key cytokines (e.g., IFN-γ, IL-2, IL-4, IL-10) and improving immune function in animal models.


4
Cognitive and Renal Protection
https://www.sciencedirect.com/science/article/abs/pii/S0378874118347147

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Amelioration of Cognitive Impairment in Chronic Renal Failure

Studies in animal models of chronic renal failure show that aqueous extracts of You Gui Yin improve cognitive function, likely through anti-inflammatory and neuroprotective mechanisms.


For You Gui Wan, take 3 tablets 2 times per day. These should be taken before or after meal.

Total pieces in package: 120 tablets

Dosage: 3 tablets

Frequency: 2 times a day before or after meal


Side effects

Dampness

Digestive discomfort

Heat sensation

Overstimulation


Allergies

Individuals allergic to any of the herbal ingredients should avoid use. Discontinue immediately if any allergic reactions, such as rash, itching, or swelling, occur.

Cinnamon

Rehmannia Root Allergy


Avoid medicine interactions

Anticoagulants or Antiplatelet Drugs

Antihypertensive Medications

Diuretics

Hormonal Therapies (hormone replacement therapy, corticosteroids)

Immunosuppressants

Sedatives or CNS-Acting Drugs


Precautions

Discontinue use if allergic reaction occurs.

Do not use if pregnant or breastfeeding.

Consult your herbalist or physician before use if you are taking other medications or receiving other medical treatments.

Consult your herbalist or doctor before use if you have high blood pressure, or if you are children, old or very weak.

Keep out of reach of children.

Do not use when you have a fever.


Indemnification

This product is a dietary supplement, and should only be used as prescribed by a qualified acupuncturist, herbalist, phyto- or TCM therapist. This product is not intended to diagnose, treat, prevent or cure any disease. Always consult a qualified doctor or healthcare professional before using this. A healthy lifestyle is important, as is a varied, balanced diet, for which supplements are not a substitute.

TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. 1 packing adviced and then evaluate with your prescriber!

Allergies

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