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Li Zhong Wan

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Zhenatura Li Zhong Wan Extra Strong is a traditional Chinese herbal preparation formulated according to the principles of Traditional Chinese Medicine (TCM). This classical formula features key botanical ingredients such as Ginseng root (Ren Shen) or Codonopsis root (Dang Shen), Atractylodes rhizome (Bai Zhu), Dried Ginger (Gan Jiang), and Licorice root (Zhi Gan Cao). These herbs are traditionally valued for their warming properties and their ability to support the digestive system and promote inner vitality. Ginseng and Atractylodes help to nourish energy (Qi) and strengthen the digestive center, while Dried Ginger is used to gently warm the body and dispel internal cold. Licorice root harmonizes the entire blend and supports overall balance. Together, these ingredients support healthy digestion, comfort in the abdomen, and physical warmth.

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This product is sold exclusively as a dietary supplement. It is not a medicine. Its use is based on traditional TCM applications.

Main benefits

  • Pattern Identification: Traditionally used for the TCM pattern of Spleen and Stomach Deficient Cold (Middle Jiao Cold), characterized by watery diarrhea, vomiting, poor appetite, abdominal pain that is relieved by warmth and pressure, cold extremities, and an absence of thirst.

  • Core Function: The formula is classically said to warm the middle jiao, dispel Cold, tonify Qi, and strengthen the Spleen and Stomach.

  • Deficiency and Cold Relationship: Based on the TCM principle that "Deficiency of Spleen Yang generates internal Cold," the formula addresses the root weakness of the digestive fire while simultaneously driving out the accumulated Cold that causes abdominal cramping and diarrhea.

  • Key Ingredients: Gan Jiang (Dried Ginger) strongly warms the middle jiao to dispel internal Cold; Ren Shen (Ginseng) tonifies primal Qi and deeply nourishes the Spleen; Bai Zhu (Atractylodes) strengthens Spleen Qi and dries Dampness to stop diarrhea; Zhi Gan Cao (Honey-fried Licorice) harmonizes the ingredients and tonifies middle Qi; while Corn Starch serves as a modern excipient for pill/tablet binding.

  • Digestive Component (TCM): Often used when gastrointestinal distress is triggered or aggravated by consuming cold or raw foods, or by exposure to cold environments, reflecting the compromised Yang energy of the digestive system.

  • Region of Action: Primarily targets the middle jiao—specifically the Spleen, Stomach, and abdomen—the body's central hub for digesting food and transforming it into usable Qi and Blood.

  • Classical Heritage: First recorded in the Han-dynasty classic Shang Han Lun (Treatise on Cold Damage) by Zhang Zhong-Jing, it is the archetypal formula for treating gastrointestinal disorders caused by internal Cold and Yang deficiency.

Zhenatura.com TCM: Herbal dietary supplements of Traditional Chinese Medicine origine according to European standards!

  • Strength 10:1
  • 120 tablets per bottle
  • Double or Triple the strength as regular brands
  • Less fillers and binders
  • No pharmaceuticals or dyes
  • Thorough lab testing (heavy metals, pesticides etc.)
  • Always made in controlled cGMP certified facility
  • Unbeatable value
  • European brand
TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. We advice always to use minimum 1 packing and then evaluate with your prescriber!
This product is a dietary (food) supplement, to be taken as directed by a qualified practitioner. It is not intended to treat, cure, diagnose or prevent any disease. Not to replace a varied diet. Not to be taken if nursing or if pregnant. Not to be consumed continuously for longer than 3 months.

Common uses

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Information for professionals

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Zhenatura Li Zhong Wan Extra Strong is based on the classical Li Zhong Wan (“Regulate the Middle Pill”), first recorded in the Han-dynasty medical text Shang Han Lun (“Treatise on Cold Damage”) by the renowned physician Zhang Zhong-jing. Within traditional Chinese herbal literature, this specific combination of botanicals—including Ginseng Root, Honey-prepared Licorice Root, Largehead Atractylodes Rhizome, and Dried Ginger—was described as a method to “warm the Middle Jiao,” “strengthen the Spleen,” and “dispel Cold” in accordance with the TCM theoretical framework. These descriptions belong exclusively to the traditional conceptual system of Chinese medicine and do not refer to modern anatomy, psychology, or scientifically validated physiological effects.

Asian Ginseng Root (Ren Shen)

Asian Ginseng Root (Ren Shen)

Atractylodes Rhizome (Bai Zhu)

Atractylodes Rhizome (Bai Zhu)

Corn Starch (Yù mǐ diàn fěn)

Corn Starch (Yù mǐ diàn fěn)

Dried Ginger Rhizome (Gan Jiang)

Dried Ginger Rhizome (Gan Jiang)

Processed Licorice Root (Zhi Gan Cao)

Processed Licorice Root (Zhi Gan Cao)

1
Chronic Diarrhea and IBS-D — Remodeling the Gut Microbiota
https://asante-academy.com/encyclopedia/li-zhong-wan/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

The primary modern clinical application for Li Zhong Wan (and its variant Fu Zi Li Zhong Wan) is the treatment of chronic, debilitating digestive disorders, particularly diarrhea-predominant Irritable Bowel Syndrome (IBS-D) and chronic, watery diarrhea.

Modern pharmacological and clinical research indicates that the formula works largely by remodeling the gut microbiome. A recent study utilizing network pharmacology and microbiota profiling demonstrated that Fu Zi Li Zhong Wan significantly altered the bacterial composition in the gut of IBS-D patients. By intensely warming the digestive tract and drying excess dampness, the formula creates a hostile environment for pathogenic bacteria that thrive in cold, stagnant, fluid-filled intestines, while actively promoting the growth of beneficial, mucosal-repairing bacteria. This stops the chronic leakage of fluids into the bowels and drastically reduces the urgency and frequency of diarrhea.

2
Gastritis, Peptic Ulcers, and Abdominal Pain — Healing the Mucosa
https://www.aompress.com/resources/pdfs/book-formulas/Sample_Monograph_Li_Zhong_Wan.pdf

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Because of its ability to "Regulate the Middle," the formula is widely used for chronic, cold-type gastritis, gastric ulcers, and generalized stomach pain.

In these conditions, the patient typically complains of a dull, gnawing pain in the stomach that gets worse after eating cold food or drinking cold water, and feels better when a hot water bottle is applied. Clinical trials involving Li Zhong Wan (often administered as a warm decoction for faster absorption in acute pain) report high efficacy rates for complete pain relief in patients with peptic ulcers and chronic gastroenteritis. The Ren Shen and Zhi Gan Cao protect and heal the inflamed gastric mucosa, while Gan Jiang increases localized blood flow (microcirculation) to the stomach lining, physically warming the tissue to resolve the ischemic (cold) pain and promote ulcer healing.

3
Diabetes and Metabolic Disorders — Restoring the Spleen
https://pmc.ncbi.nlm.nih.gov/articles/PMC4609429/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

In integrative clinical practice, Li Zhong Wan (particularly the Fu Zi variant) is frequently utilized as a foundational treatment for Type 2 Diabetes and associated metabolic disorders when the patient exhibits profound "Yang Deficiency."

In TCM, the Spleen is responsible for transforming food into usable energy. When the Spleen Yang collapses, sugar/energy accumulates improperly in the blood rather than being transported to the muscles, leading to exhaustion, coldness, and high blood sugar. By aggressively warming the metabolic center and fortifying the Spleen, the formula helps restore insulin sensitivity and proper cellular glucose uptake, improving overall metabolic function in diabetic patients.

For Li Zhong Wan, take 3 tablets 2 times per day. These should be taken before or after meal.

Total pieces in package: 120 tablets

Dosage: 3 tablets

Frequency: 2 times a day before or after meal

Do not exceed the recommended daily dose. This supplement is not a substitute for a balanced diet.

Side effects

No known side effects.

Allergies

Individuals allergic to any of the herbal ingredients should avoid use. Discontinue immediately if any allergic reactions, such as rash, itching, or swelling, occur.

No known allergies.

Avoid medicine interactions

No known medicine interactions.

Precautions

Consult your doctor if taking medicines or under medical care.

Not recommended with stomach or intestinal problems.

Do not use in case of fever or acute infection.

Not suitable for people with high blood pressure.

Do not use if pregnant or breastfeeding.

Stop use at least two weeks before surgery.

Indemnification

This product is a dietary supplement, and should only be used as prescribed by a qualified acupuncturist, herbalist, phyto- or TCM therapist. This product is not intended to diagnose, treat, prevent or cure any disease. Always consult a qualified doctor or healthcare professional before using this. A healthy lifestyle is important, as is a varied, balanced diet, for which supplements are not a substitute.

TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. 1 packing adviced and then evaluate with your prescriber!

Formula types

Ingredients

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Ingredients Pinyin

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Original classical patents

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Original classical patents Pinyin

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SKU: ZHEN0238

GTIN: 8721472362695