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This product is sold exclusively as a dietary supplement. It is not a medicine. Its use is based on traditional TCM applications.

Main benefits

  • Pattern Identification: Traditionally used for the TCM pattern of “Shao Yang Disharmony with Heat Above and Cold Below,” characterized by alternating chills and fever, irritability, dry mouth, and bitter taste, accompanied by abdominal coldness, poor digestion, loose stools, and fluid retention (such as thirst with no desire to drink).

  • Upper Heat & Lower Cold Rebalancing: Expertly formuated to harmonize the energetic pivot by clearing constrained Heat from the upper body (chest, Liver, and Gallbladder) while simultaneously warming the Middle Jiao to dispel trapped Cold and dampness in the digestive tract.

  • Fluid & Water Regulation: Gan Jiang and Gui Zhi work together to warm the channels and transform lingering cold fluids, addressing symptoms like splashing sounds in the stomach, water retention, and urinary difficulty caused by deficient internal Yang.

  • Shen (Spirit) Calming: The inclusion of heavy, mineral-based Mu Li helps to anchor floating Yang and calm the mind, providing deep relief from anxiety, palpitations, insomnia, and restlessness associated with constrained Shao Yang Fire.

  • Fluid Generation & Dryness Relief: Gua Lou Gen effectively clears upper Heat and generates body fluids, healing a dry mouth, dry throat, and thirst, which perfectly balances the warming and drying nature of the ginger and cinnamon.

  • Liver & Digestive Harmony: Bridges the gap between Liver tension and Spleen/Stomach weakness, making it highly suitable for stress-related digestive issues, menopausal temperature fluctuations, or complex post-viral fatigue presenting with mixed hot and cold signs.

  • Classical Heritage: A brilliant modification from Zhang Zhongjing’s 3rd-century Shang Han Lun (Treatise on Cold Damage), historically revered for resolving complex "half-exterior, half-interior" conditions complicated by pre-existing digestive cold and fluid stagnation


Zhenatura.com TCM: Herbal dietary supplements of Traditional Chinese Medicine origine according to European standards!

  • Strength 10:1
  • 120 tablets per bottle
  • Double or Triple the strength as regular brands
  • Less fillers and binders
  • No pharmaceuticals or dyes
  • Thorough lab testing (heavy metals, pesticides etc.)
  • Always made in controlled cGMP certified facility
  • Unbeatable value
  • European brand
TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. We advice always to use minimum 1 packing and then evaluate with your prescriber!
This product is a dietary (food) supplement, to be taken as directed by a qualified practitioner. It is not intended to treat, cure, diagnose or prevent any disease. Not to replace a varied diet. Not to be taken if nursing or if pregnant. Not to be consumed continuously for longer than 3 months.

Common uses

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Information for professionals

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Zhenatura Chai Hu Gui Zhi Gan Jiang Tang Extra Strong is based on the classical Chai Hu Gui Zhi Gan Jiang Tang (“Bupleurum, Cinnamon Twig and Ginger Decoction”), first attributed to the Eastern Han physician Zhang Zhong‑jing in his Shang Han Za Bing Lun (“Treatise on Cold Damage and Miscellaneous Diseases”). Within traditional Chinese herbal literature, formulas of this type—built around Radix Bupleuri (Chai Hu), Ramulus Cinnamomi (Gui Zhi), Radix Scutellariae (Huang Qin), Rhizoma Zingiberis (Gan Jiang), Concha Ostreae (Mu Li), Radix Glycyrrhizae (Gan Cao), and Radix Trichosanthis (Gua Lou Gen), and in modern supplements prepared on a neutral base such as corn starch—are described as methods to “harmonize the Shaoyang,” “warm Yang and transform retained Fluids,” and “soften hardness and calm constraint” according to the TCM theoretical framework. These descriptions belong exclusively to the traditional conceptual system of Chinese medicine and do not refer to modern cardiology, psychiatry, immunology, or scientifically validated physiological effects.

1
Peri- and Post-Menopausal Depression and Insomnia — Harmonizing Shao Yang and Soothing Stress
https://pubmed.ncbi.nlm.nih.gov/16265982/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

A significant area of modern clinical research for Chai Hu Gui Zhi Gan Jiang Tang involves its efficacy in treating stress pathways and mood disorders, particularly during menopause. A notable 2005 clinical trial investigated its effects on climacteric women suffering from both insomnia and depressed mood compared to standard anti-depressants.

The researchers measured blood plasma levels of Interleukin-6 (IL-6) and soluble Interleukin-6 receptor (sIL-6R)—biomarkers strongly linked to chronic stress, inflammation, and depressive symptoms. After three months of treatment, the group receiving the herbal formula showed a significant decrease in IL-6 (-34.8%) and sIL-6R (-22.4%), which conventional anti-depressants failed to reduce. The reduction of these inflammatory stress markers strongly correlated with improvements in the patients' Hamilton depression scores.

In TCM, severe insomnia, mood swings, and menopausal hot flashes are often viewed as a Shao Yang disharmony where internal heat (stress/hormonal changes) rises, but the core energy (Spleen) is weak and cold. By harmonizing this upper-heat/lower-cold dynamic, the formula effectively "soothes" the Liver/Gallbladder to stop the hyperactive stress response and anchors the mind to permit deep sleep.


2
Complex Gastrointestinal Disorders — Clearing Upper Heat and Warming Spleen Cold
https://www.hjmedicalgroup.com/en/post/chai-hu-gui-zhi-gan-jiang-tang-a-tcm-remedy-for-shaoyang-disorders-and-fluid-retention

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

The formula is a premier choice for patients suffering from what TCM calls "Liver attacking the Spleen," where stress or a lingering illness has caused heat in the Gallbladder but destroyed the digestive fire. This often looks clinically similar to Irritable Bowel Syndrome (IBS) or chronic post-infectious diarrhea.

While large Western pharmacological trials are sparse, traditional clinical data heavily supports its use when a patient has upper digestive tightness (chest/rib fullness) but lower digestive coldness (chronic diarrhea). Gan Jiang and Gui Zhi work pharmacologically to stimulate gastric mucosal blood flow and increase digestive enzyme secretion (warming the Spleen), while Chai Hu and Huang Qin provide anti-inflammatory and hepatoprotective effects to calm the upper GI tract.


3
Resolution of Fluid Retention and Cysts — Dissipating Nodules
https://www.hjmedicalgroup.com/en/post/chai-hu-gui-zhi-gan-jiang-tang-a-tcm-remedy-for-shaoyang-disorders-and-fluid-retention

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Another traditional but vital application is for patients with "fluid retention" that causes physical tightness or palpable nodules in the chest, ribs, or neck (such as swollen lymph nodes or mild thyroid nodules).

The combination of Mu Li (Oyster Shell) and Tian Hua Fen (Trichosanthes root) works synergistically to "soften hardness and dissipate nodules." Pharmacologically, oyster shell is rich in calcium carbonate and trace minerals, which in TCM theory possess a heavy, descending nature that anchors floating Yang and breaks up chronic phlegm/fluid deposits caused by a stagnant lymphatic or fluid system.

For Chai Hu Gui Zhi Gan Jiang Tang, take 3 tablets 2 times per day. These should be taken before or after meal.

Total pieces in package: 120 tablets

Dosage: 3 tablets

Frequency: 2 times a day before or after meal

Do not exceed the recommended daily dose. This supplement is not a substitute for a balanced diet.


Side effects

No known side effects.


Allergies

Individuals allergic to any of the herbal ingredients should avoid use. Discontinue immediately if any allergic reactions, such as rash, itching, or swelling, occur.

Molluscs


Avoid medicine interactions

No known medicine interactions.


Precautions

Stop use at least two weeks before surgery.

Not suitable for people with high blood pressure.

Consult your doctor if taking medicines or under medical care.

Not recommended with stomach or intestinal problems.

Do not use if pregnant or breastfeeding.


Indemnification

This product is a dietary supplement, and should only be used as prescribed by a qualified acupuncturist, herbalist, phyto- or TCM therapist. This product is not intended to diagnose, treat, prevent or cure any disease. Always consult a qualified doctor or healthcare professional before using this. A healthy lifestyle is important, as is a varied, balanced diet, for which supplements are not a substitute.

TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. 1 packing adviced and then evaluate with your prescriber!

Allergies

Formula types

Ingredients

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Ingredients Pinyin

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Original classical patents

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Original classical patents Pinyin

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SKU: ZHEN0251

GTIN: 8721472362855