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This product is sold exclusively as a dietary supplement. It is not a medicine. Its use is based on traditional TCM applications.

Main benefits

  • Pattern Identification: Traditionally used for the TCM pattern of “Concurrent Tai Yang (Exterior) and Shao Yang (Half-Exterior, Half-Interior) Disharmony,” characterized by mild chills and fever, joint and muscle aches, stiffness, headache, accompanied by chest or rib fullness, mild nausea, poor appetite, and a bitter taste in the mouth.

  • Harmonize & Release Action: Brilliantly combines the exterior-releasing properties of Cinnamon Twig Decoction (Gui Zhi Tang) with the pivot-harmonizing effects of Minor Bupleurum Decoction (Xiao Chai Hu Tang), gently pushing pathogens out from both the superficial muscle layer and the energetic pivot without causing excessive sweating.

  • Ying & Wei Regulation: Gui Zhi and Shao Yao work perfectly together to harmonize the Nutritive (Ying) and Defensive (Wei) Qi, promoting a very mild, regulating sweat that relieves muscle tension, joint aches, and stiffness associated with lingering exterior wind-cold.

  • Shao Yang Clearance: Chai Hu and Huang Qin clear constrained Heat from the Liver and Gallbladder channels, alleviating the alternating sensations of cold and heat, chest tightness, irritability, and bitter taste that occur when a pathogen is stuck halfway in the body.

  • Digestive & Nausea Relief: Zhi Ban Xia and Sheng Jiang help to transform Phlegm, warm the Middle, and descend rebellious Stomach Qi, effectively resolving the mild nausea, upset stomach, or loss of appetite that frequently accompanies this mixed pattern.

  • Qi & Middle Jiao Support: Ren Shen, Da Zao, and Gan Cao tonify Spleen and Stomach Qi, boosting the body's Upright (immune) Qi to prevent the pathogen from penetrating deeper into the interior while supporting overall recovery and energy levels.

  • Classical Heritage: A legendary 3rd-century prescription from Zhang Zhongjing’s Shang Han Lun (Treatise on Cold Damage), revered for its elegant ability to resolve complex, lingering colds or systemic imbalances that present with both surface body aches and internal digestive or chest symptoms.


Zhenatura.com TCM: Herbal dietary supplements of Traditional Chinese Medicine origine according to European standards!

  • Strength 10:1
  • 120 tablets per bottle
  • Double or Triple the strength as regular brands
  • Less fillers and binders
  • No pharmaceuticals or dyes
  • Thorough lab testing (heavy metals, pesticides etc.)
  • Always made in controlled cGMP certified facility
  • Unbeatable value
  • European brand
TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. We advice always to use minimum 1 packing and then evaluate with your prescriber!
This product is a dietary (food) supplement, to be taken as directed by a qualified practitioner. It is not intended to treat, cure, diagnose or prevent any disease. Not to replace a varied diet. Not to be taken if nursing or if pregnant. Not to be consumed continuously for longer than 3 months.

Common uses

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Information for professionals

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Zhenatura Chai Hu Gui Zhi Tang Extra Strong is based on the classical Chai Hu Gui Zhi Tang (“Bupleurum and Cinnamon Twig Decoction”), first attributed to the Eastern Han physician Zhang Zhong‑jing in the Shang Han Lun (“Treatise on Cold Damage Diseases”). It is traditionally described as a combination of two foundational prescriptions—Xiao Chai Hu Tang and Gui Zhi Tang—each used at reduced dosage to address lingering exterior symptoms together with Shaoyang‑layer disharmony. Within traditional Chinese herbal literature, the version composed of Radix Bupleuri (Chai Hu), Rhizoma Pinelliae praeparatum (Zhi Ban Xia), Ramulus Cinnamomi (Gui Zhi), Radix Paeoniae alba (Shao Yao), Radix Scutellariae (Huang Qin), Fructus Jujubae (Da Zao), Radix Ginseng (Ren Shen), Radix Glycyrrhizae (Gan Cao), Rhizoma Zingiberis recens (Sheng Jiang), and in modern supplements a neutral base such as corn starch, is described as a method to “harmonize Taiyang and Shaoyang,” “release residual Wind‑Cold from the exterior,” and “support Qi while clearing constrained Heat” according to the TCM theoretical framework. These descriptions belong exclusively to the traditional conceptual system of Chinese medicine and do not refer to modern infectious‑disease models, immunology, or scientifically validated physiological effects.

1
Gastrointestinal Ulcers and Hepatobiliary Disorders — Harmonizing Liver and Spleen
https://www.sciencedirect.com/science/article/abs/pii/S0304383599004292

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

A major clinical application of Chai Hu Gui Zhi Tang is for upper digestive issues, specifically gastric ulcers, cholecystitis, and hepatitis.

Pre-clinical studies and pharmacological research have demonstrated that the formula exerts significant anti-ulcerative and hepatoprotective effects. For instance, in rat models, Saikokeishito (the Japanese Kampo equivalent) has been shown to prevent gut ischemia/reperfusion-induced liver injury via the modulation of nitric oxide. Furthermore, research indicates it suppresses the development of experimentally induced liver lesions and pre-cancerous hepatic foci, likely due to the anti-inflammatory properties of Chai Hu (Bupleuri Radix).

In TCM, gastric ulcers and upper abdominal pain are often diagnosed as "Liver overacting on the Spleen/Stomach." When Qi stagnates in the Liver (causing rib-side tightness), it attacks the stomach (causing ulcers and nausea). Chai Hu unblocks the Liver Qi, while Shao Yao and Gan Cao relieve painful abdominal cramping.


2
Allergic Rhinitis — Venting Pathogens
https://pubmed.ncbi.nlm.nih.gov/40207407/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Recent advances in pharmacological network analysis have begun exploring the formula's mechanism in treating allergic rhinitis. A 2025 study utilized mass spectrometry and machine learning to identify the active compounds in Chai Hu Gui Zhi Tang. The research revealed that compounds within the formula (such as cinnamic acid from Gui Zhi) act on immune-related genes (like Interleukin-4 and IL-5) to combat allergic responses and modulate the metabolism of foreign substances.

In TCM, allergies are a form of "Wind" trapped in the exterior. Because the formula combines surface-releasing herbs (Gui Zhi) with heat-clearing and immune-modulating herbs (Chai Hu, Huang Qin), it physically pushes the trapped allergic pathogen outward while reducing localized inflammation.


3
Neuralgia, Muscle Pain, and Epilepsy — Releasing the Exterior and Relieving Spasms
https://yinyanghouse.com/theory/theory/herbalmedicine/tcm-formulas/chai-hu-gui-zhi-tang-wan-bupleurum-cinnamon-twig-decoction/

Please note: This summary is a concise interpretation of the original article; please refer to the source for the full context and details.

Clinically, the formula is highly utilized for nerve and muscle pain that follows a viral infection, such as intercostal neuralgia, trigeminal neuralgia, and frozen shoulder. The combination of Gui Zhi (cinnamon twig) to warm the channels and Shao Yao (peony) to nourish the blood is famous in TCM for stopping muscle spasms.

Additionally, Japanese clinical research has historically used Saikokeishito as an adjunct treatment for epilepsy. The formula's ability to soothe the Liver (which "governs" the tendons and spasms in TCM) and clear phlegm-heat makes it a stabilizing agent for the nervous system, reducing the frequency of mild seizures when combined with conventional anti-epileptics.

For Chai Hu Gui Zhi Tang, take 3 tablets 2 times per day. These should be taken before or after meal.

Total pieces in package: 120 tablets

Dosage: 3 tablets

Frequency: 2 times a day before or after meal

Do not exceed the recommended daily dose. This supplement is not a substitute for a balanced diet.


Side effects

No known side effects.


Allergies

Individuals allergic to any of the herbal ingredients should avoid use. Discontinue immediately if any allergic reactions, such as rash, itching, or swelling, occur.

No known allergies.


Avoid medicine interactions

No known medicine interactions.


Precautions

Not suitable for people with high blood pressure.

Consult your doctor if taking medicines or under medical care.

Not recommended with stomach or intestinal problems.

Do not use if pregnant or breastfeeding.


Indemnification

This product is a dietary supplement, and should only be used as prescribed by a qualified acupuncturist, herbalist, phyto- or TCM therapist. This product is not intended to diagnose, treat, prevent or cure any disease. Always consult a qualified doctor or healthcare professional before using this. A healthy lifestyle is important, as is a varied, balanced diet, for which supplements are not a substitute.

TCM traditional Chinese Patents do not work immediate, it takes some time before you (and your organs) will experiences the benefits. 1 packing adviced and then evaluate with your prescriber!

Formula types

Ingredients

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Ingredients Pinyin

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Original classical patents

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Original classical patents Pinyin

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SKU: ZHEN0252

GTIN: 8721472362862

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